Hippocampal Atrophy in Major Depression: a Function of Childhood Maltreatment Rather than Diagnosis?
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چکیده
منابع مشابه
Childhood maltreatment and adult proinflammatory status in patients with major depression.
BACKGROUND An increasing body of research considers the immunological effects of major depression. It remains an open question, whether depression itself acts in an immunomodulatory fashion or whether other factors related to depression result in these immunological effects. Regardless, major depression is often the result of early life stress, the implications of which are not satisfactorily u...
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15 صفحه اولCourse of illness, hippocampal function, and hippocampal volume in major depression.
Studies have examined hippocampal function and volume in depressed subjects, but none have systematically compared never-treated first-episode patients with those who have had multiple episodes. We sought to compare hippocampal function, as assessed by performance on hippocampal-dependent recollection memory tests, and hippocampal volumes, as measured in a 1.5-T magnetic resonance imager, in de...
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Background and Aim: For effective treatment of Alzheimer's disease (AD), it is important to accurately diagnosis of AD and its earlier stage, Mild Cognitive Impairment (MCI). One of the most important approaches of early detection of AD is to measure atrophy, which uses various kinds of brain scans, such as MRI. The main objective of the current research was to provide a computerized diagnostic...
متن کاملHippocampal volume reduction in major depression.
OBJECTIVE Elevated levels of glucocorticoids in depression have been hypothesized to be associated with damage to the hippocampus, a brain area involved in learning and memory. The purpose of this study was to measure hippocampal volume in patients with depression. METHOD Magnetic resonance imaging was used to measure the volume of the hippocampus in 16 patients with major depression in remis...
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ژورنال
عنوان ژورنال: Neuropsychopharmacology
سال: 2014
ISSN: 0893-133X,1740-634X
DOI: 10.1038/npp.2014.145